Kastorini, C-M., et al. (2011). The effect of Mediterranean diet on metabolic syndrome and its components: a meta-analysis of 50 studies and 534,906 individuals. J Am Coll Cardiol, 57, 1299-1313.
Background: The Mediterranean diet has long been associated with low cardiovascular disease risk in adult population.
Results: The combined effect of prospective studies and clinical trials showed that adherence to the Mediterranean diet was associated with reduced risk of metabolic syndrome. Additionally, results from clinical studies revealed the protective role of the Mediterranean diet on components of metabolic syndrome, like waist circumference, high-density lipoprotein cholesterol, triglycerides, blood pressure, and glucose, whereas results from epidemiological studies also confirmed those of clinical trials.
Conclusions: These results are of considerable public health importance, because this dietary pattern can be easily adopted by all population groups and various cultures and cost-effectively serve for primary and secondary prevention of the metabolic and its individual components.